Dimethylamine → SBB061064

HRID 444188

反応式

HRID 444188 の反応式
Cl[CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][OH:10].[CH3:11][NH:12][CH3:13]>>[CH3:11][N:12]([CH3:13])[CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][OH:10]

参加物

3

反応物 2

HCID 674DimethylamineHCID 788712-(2-(2-Chloroethoxy)ethoxy)ethanol

生成物 1

HCID 10845034SBB061064

実験手順

Commercial Cl(CH2CH2O)3H (abb. ClE3H) (2.0 mole) and dimethylamine (20.0 mole) were mixed in a flask (3.0 l) fitted with a condenser and stirred (RT) for 30 hours. TLC (Si-gel) examination showed the complete consumption of the ClE3H. Excess dimethylamine was removed by two consecutive evaporations under reduced pressure. The residual material was reconstituted in CHCl3, dried (MgSO4), filtered and evaporated to dryness to produce the product, 8-dimethylamino-3,6-dioxaoctanol.

後処理

  1. customfitted with a condenser
  2. customthe complete consumption of the ClE3H
  3. customExcess dimethylamine was removed by two consecutive evaporations under reduced pressure
  4. dry with materialdried (MgSO4)
  5. filtrationfiltered
  6. customevaporated to dryness

出典と根拠

ORDレコード
ord-640529c8258d4e74a8dd8c70eedc4121
出典データセット
uspto-grants-1981_04
特許番号
US04263281

関連ノート

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