Formamide → 2-Formamidotridecane

HRID 444247

反応式

HRID 444247 の反応式
[CH2:1]([C:12]([CH3:14])=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[CH:15]([NH2:17])=[O:16]>C(O)=O>[CH:15]([NH:17][CH:12]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH3:14])=[O:16]

参加物

4

反応物 2

HCID 713FormamideHCID 116222-Tridecanone

生成物 1

HCID 217010542-Formamidotridecane

試薬・触媒・溶媒 1

HCID 284Formic Acid溶媒

反応条件

温度
160 °C

実験手順

70 g of methyl undecyl ketone are added to 250 ml of formamide. The mixture is heated, with constant stirring, to 160° C. Then 40 ml of formic acid are added dropwise in the course of 24 hours. The reaction mixture is cooled, poured on ice, extracted with ether and the ethereal extract is dried over Na2SO4. After distilling off the ether, the oily residue is distilled in vacuo, affording 60 g of 2-formamidotridecane. Boiling point: 145°-155° C./0.01.

後処理

  1. temperatureThe reaction mixture is cooled
  2. additionpoured on ice
  3. extractionextracted with ether
  4. extractionthe ethereal extract
  5. dry with materialis dried over Na2SO4
  6. distillationAfter distilling off the ether
  7. distillationthe oily residue is distilled in vacuo

出典と根拠

ORDレコード
ord-6418589092854135addf7e409ec13f14
出典データセット
uspto-grants-1981_04
特許番号
US04263324

関連ノート

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