Phthalimide → N-Aminophthalimide

HRID 444386

反応式

HRID 444386 の反応式
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[NH2:12]N>C(O)C>[NH2:12][N:5]1[C:1](=[O:11])[C:2]2[C:3](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4]1=[O:6]

参加物

4

反応物 2

HCID 6809PhthalimideHCID 9321Hydrazine

生成物 1

HCID 74645N-Aminophthalimide収率 75.2%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To an ice-cold suspension of 14.7 g (0.1 mole) of phthalimide in 100 ml of 95% ethyl alcohol at 5° C., with stirring, 3.6 ml (0.11 mole) of 96.8% hydrazine was added dropwise. A slight exothermic reaction was observed and the mixture was allowed to stir at 5° C. for two hours. The mixture was diluted with 200 ml of ice water, stirred, filtered, washed with water and dried to give 12.2 g (75%) of white powder, m.p. 199°-202°.

後処理

  1. customA slight exothermic reaction
  2. stirringto stir at 5° C. for two hours
  3. stirringstirred
  4. filtrationfiltered
  5. washwashed with water
  6. customdried

出典と根拠

ORDレコード
ord-278d329dd7d84b89a0140ad822e6d942
出典データセット
uspto-grants-1981_04
特許番号
US04264502

関連ノート

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