Methylhydrazine → N,1-Dimethyl-N-phenylhydrazinethiocarboxamide
反応式
[CH3:1][N:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3](Cl)=[S:4].[CH3:12][NH:13][NH2:14]>CCOCC>[CH3:1][N:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3]([N:13]([CH3:12])[NH2:14])=[S:4]参加物
4
実験手順
To a solution of N-methyl-N-phenylthiocarbamyl chloride 79.6 g (0.43 m) in 250 ml dry ether, a solution of 39.5 g (0.86 m) methylhydrazine in 100 ml of dry ether was added dropwise with stirring below 10° C. The reaction temperature was allowed to increase to room temperature and filtered. The filtrate was evaporated to low volume and diluted with ~300 ml hexane. After stirring for a few hours the hexane layer was decanted. The hexane immiscible layer was reevacuated to remove organic solvents, giving the desired product, 70.0 g as a thick orange liquid.
後処理
- filtrationfiltered
- customThe filtrate was evaporated to low volume
- additiondiluted with ~300 ml hexane
- stirringAfter stirring for a few hours the hexane layer
- customwas decanted
- customto remove organic solvents
出典と根拠
- ORDレコード
- ord-715f2e5bab204598ae2eeb113c0c7965
- 出典データセット
- uspto-grants-1981_04
- 特許番号
- US04264502
反応ノート
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