化工社化工社 化学情報印刷レポート · 研究参考用
(4-Chloro-2-methylphenyl)boronic acid → 3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Chloro-2-methylphenyl)boronic acid | HCID 5017600 | — |
| 反応物 | Methyl 3-amino-6-bromo-5-(trifluoromethyl)picolinate | HCID 58964428 | — |
| 生成物 | 3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid | HCID 68169540 | — |
反応手順
This compound was prepared from 3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester (Intermediate A4) and 4-chloro-2-methylphenylboronic acid analogously to Intermediate H; LC-MS Rt=1.53 mins, [M+H]+ 331 (Method 2 min LC_v002).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08476269B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-6e675906c96b4adb9caa95d8fc401b9b |
| 出典メモ | uspto-grants-2013_07 |