化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → 2-(5-Bromo-pyridin-3-yl)-N-methyl-acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Methylamine | HCID 6329 | — |
| 反応物 | 2-(5-Bromopyridin-3-yl)acetic acid | HCID 2802539 | — |
| 生成物 | 2-(5-Bromo-pyridin-3-yl)-N-methyl-acetamide | HCID 54236812 | — |
反応手順
The title compound was synthesized in a similar manner as described for Example 103 using (5-bromo-pyridin-3-yl)-acetic acid (ABCR, Karlsruhe, Germany, 1.815 mmol) and 8 M methylamine in EtOH (Aldrich, Buchs, Switzerland, 7.26 mmol) to give the title compound as an off-white solid. (HPLC: tR 1.74 min (Method A); M+H=229, 231 MS-ES)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08476294B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-2a07b27fc62142d5a8c6f5ad95515fb3 |
| 出典メモ | uspto-grants-2013_07 |