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Triphenylphosphine → Phosphonium, (1,2-diethoxy-2-oxoethyl)triphenyl-, chloride (1:1)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | Ethyl 2-chloro-2-ethoxyacetate | HCID 2724873 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | Phosphonium, (1,2-diethoxy-2-oxoethyl)triphenyl-, chloride (1:1) | HCID 11327835 | 82% |
反応手順
To a solution of 2-chloro-2-ethoxyacetic acid ethyl ester (10 g, 60 mmol) in chloroform (30 mL) was added triphenylphosphine (15.7 g, 60 mmol) and stirred overnight at room temperature. The solvent was removed in vacuo, and diethyl ether was added. The solvent was again removed and dried on high vacuum to give (1,2-diethoxy-2-oxoethyl)triphenylphosphonium chloride (21 g, 82% yield) (679) as a foamy solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08476308B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-2b9a860869ac44618919f38e159b26dd |
| 出典メモ | uspto-grants-2013_07 |