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2,6-Lutidine → 2,6-Dimethylpyridine N-oxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Lutidine | HCID 7937 | — |
| 反応物 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 2,6-Dimethylpyridine N-oxide | HCID 14083 | 88.4% |
反応手順
To a 0° C. solution of 2,6-dimethylpyridine (1.0 g, 0.009 mol) in CHCl3 (25 mL) was added mCPBA (3.17 g, 0.01 mol). The reaction mixture was then stirred for 12 h at RT, quenched with a saturated Na2CO3 solution. The organic layer was separated, dried over Na2SO4 and concentrated in vacuo to afford 2,6-dimethylpyridine 1-oxide (980 mg, 85%) as a solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08481534B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-5694c3e4dc404594a53163c478a732f0 |
| 出典メモ | uspto-grants-2013_07 |