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[1-(4-fluoro-phenyl)-2-methyl-1H-imidazol-4-yl]-methanol → 1-(4-fluoro-phenyl)-2-methyl-1H-imidazole-4-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | [1-(4-fluoro-phenyl)-2-methyl-1H-imidazol-4-yl]-methanol | HCID 67303957 | — |
| 触媒 | Manganese | HCID 23930 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(4-fluoro-phenyl)-2-methyl-1H-imidazole-4-carbaldehyde | HCID 85997993 | — |
反応手順
[1-(4-Fluoro-phenyl)-2-methyl-1H-imidazol-4-yl]-methanol is dissolved in methylene chloride. Mangan (IV) oxide is added and the reaction mixture is stirred at room temperature for 3 days. The suspension is filtered through a dicalite speed plus pad and the desired compound (4-fluoro-phenyl)-2-methyl-1H-imidazole-4-carbaldehyde is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08481548B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-687063cbc1674a448e4a228f4346c316 |
| 出典メモ | uspto-grants-2013_07 |