化工社化工社 化学情報印刷レポート · 研究参考用
(R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate → (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate | HCID 58405447 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate | HCID 59815009 | — |
反応手順
Intermediate C-1 was prepared similarly to the synthetic methods used to prepare Intermediate A with the exception that acetone was used instead of cyclopentanone in the reductive amination step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08541418B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-3fd893af0d6544c4821cd0d1f8d7b325 |
| 出典メモ | uspto-grants-2013_09 |