化工社化工社 化学情報印刷レポート · 研究参考用
Benzofuran-2-carboxylic acid → 1-[(2-Benzofuranylcarbonyl)amino]cyclohexanecarboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzofuran-2-carboxylic acid | HCID 10331 | — |
| 反応物 | Ethyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 11241228 | — |
| 生成物 | 1-[(2-Benzofuranylcarbonyl)amino]cyclohexanecarboxylic acid ethyl ester | HCID 57672902 | 80.3% |
反応手順
3.11 g (15 mmol) of 1-aminocyclohexanecarboxylic acid ethyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride, and 2.43 g (15 mmol) of benzofuran-2-carboxylic acid was used instead of 3-furancarboxylic acid in the process according to Reference Example 15 to obtain 3.80 g (80%) of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08481725B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-64eded0a67d5420d85f2d3e711cc863f |
| 出典メモ | uspto-grants-2013_07 |