1246210-02-5 → HCID 49779588、化合物
反応式
[F:1][C:2]1([F:11])[CH2:7][CH2:6][CH:5]([N:8]=[C:9]=[O:10])[CH2:4][CH2:3]1.Cl.[CH3:13][N:14]1[CH2:19][CH2:18][N:17]([C:20]2[CH:25]=[C:24]([C:26]3[CH:35]=[C:34]4[C:29]([CH2:30][CH2:31][NH:32][CH2:33]4)=[CH:28][CH:27]=3)[N:23]=[C:22]([NH2:36])[N:21]=2)[CH2:16][CH2:15]1>>[NH2:36][C:22]1[N:23]=[C:24]([C:26]2[CH:35]=[C:34]3[C:29]([CH2:30][CH2:31][N:32]([C:9]([NH:8][CH:5]4[CH2:4][CH2:3][C:2]([F:11])([F:1])[CH2:7][CH2:6]4)=[O:10])[CH2:33]3)=[CH:28][CH:27]=2)[CH:25]=[C:20]([N:17]2[CH2:16][CH2:15][N:14]([CH3:13])[CH2:19][CH2:18]2)[N:21]=1参加物
3
実験手順
This compound was prepared by using procedures analogous to those described for the synthesis of Example 5 starting from 1,1-difluoro-4-isocyanatocyclohexane and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=486.2.
後処理
- customThis compound was prepared
出典と根拠
- ORDレコード
- ord-61869f62c1094ea3b85dea4d844be750
- 出典データセット