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Boc-D-phenylalanine → HCID 178445950、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Boc-D-phenylalanine | HCID 637610 | — |
| 反応物 | (2R)-1-((9H-fluoren-9-ylmethoxy)carbonyl)pyrrolidine-2-carboxylic acid | HCID 688136 | — |
| 反応物 | (2R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid | HCID 978332 | — |
| 反応物 | (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid | HCID 2756111 | — |
| 反応物 | HCID 178427571 | HCID 178427571 | — |
| 生成物 | HCID 178445950 | HCID 178445950 | — |
反応手順
The compound was prepared according to the procedure described in the synthesis of compound (38). The amino acid derivatives used were Boc-D-Phe-OH, Fmoc-D-Phe-OH, Fmoc-D-Nle-OH, Fmoc-D-Arg(Pbf)-OH, and Fmoc-D-Pro-OH. Final purified synthetic peptide amide: amorphous powder, 140 mg in yield in a synthesis scale of 0.3 mmol HPLC analysis: tR=20.23 min, purity 99.7%, gradient 10% B to 30% B over 20 min; MS (MH+): expected molecular ion mass 679.4, observed 679.5.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08486894B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-14f3881804064ff59f79cf9da79c7635 |
| 出典メモ | uspto-grants-2013_07 |