化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 2-Methoxy-5-nitro-benzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2-Methoxy-5-nitrobenzoic acid | HCID 284163 | — |
| 生成物 | 2-Methoxy-5-nitro-benzoyl chloride | HCID 13719593 | 100% |
反応手順
2-Methoxy-5-nitro benzoic acid (500 mg, 2.5 mmol) was heated to reflux with thionyl chloride (5 ml) for 4 hr. The excess thionyl chloride was evaporated under reduced pressure to yield 2-methoxy-5-nitro-benzoyl chloride (0.55 g, 100%), which was used as such for the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08486962B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-89712d9cf5fb49ef82ff311ba6bb831c |
| 出典メモ | uspto-grants-2013_07 |