toluene-4-sulfonic acid (R)-2-phenylpropyl ester → ((R)-2-Fluoro-1-methyl-ethyl)-benzene

HRID 450710

反応式

HRID 450710 の反応式
[F:1][CH2:2][C@H:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH3:4].C1([C@@H](C)COS(C2C=CC(C)=CC=2)(=O)=O)C=CC=CC=1>>[F:1][CH2:2][C@@H:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH3:4]

参加物

3

反応物 2

HCID 13791929toluene-4-sulfonic acid (R)-2-phenylpropyl esterHCID 53628601((S)-2-Fluoro-1-methyl-ethyl)-benzene

生成物 1

HCID 53628603((R)-2-Fluoro-1-methyl-ethyl)-benzene

実験手順

The title compound was prepared as described above for the synthesis of ((S)-2-fluoro-1-methyl-ethyl)-benzene, but using toluene-4-sulfonic acid (R)-2-phenyl-propyl ester instead of toluene-4-sulfonic acid (S)-2-phenyl-propyl ester.

出典と根拠

ORDレコード
ord-286366fbcf8c4947a2a045d4e106f288
出典データセット
uspto-grants-2013_07
特許番号
US08486984B2

関連ノート

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