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4-(4-Methoxyphenyl)butyric acid → 2-(1-Benzofuran-5-yl)-5-[3-(4-methoxyphenyl)propyl]-1,3,4-oxadiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(4-Methoxyphenyl)butyric acid | HCID 78280 | — |
| 反応物 | 1-Benzofuran-5-carbohydrazide | HCID 68664129 | — |
| 生成物 | 2-(1-Benzofuran-5-yl)-5-[3-(4-methoxyphenyl)propyl]-1,3,4-oxadiazole | HCID 68663933 | 15% |
反応手順
In the same manner as in Example 14 and using 1-benzofuran-5-carbohydrazide instead of 1H-benzotriazole-5-carbohydrazide and 4-(4-methoxyphenyl)butyric acid instead of 3-(3-cyanophenyl)propionic acid, the title compound (yield 15%) was obtained as colorless crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08492378B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-b0702f4bdb514d6dbdadc40c0726b340 |
| 出典メモ | uspto-grants-2013_07 |