化工社化工社 化学情報印刷レポート · 研究参考用
3-Fluorobenzyl bromide → 2-[(3-Fluorobenzyl)thio]-5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Fluorobenzyl bromide | HCID 68007 | — |
| 反応物 | HCID 178504596 | HCID 178504596 | — |
| 生成物 | 2-[(3-Fluorobenzyl)thio]-5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole | HCID 68663363 | 87% |
反応手順
In the same manner as in Example 7 and using 5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole-2-thiol instead of 5-(1H-indazol-5-yl)-1,3,4-oxadiazole-2-thiol and 3-fluorobenzyl bromide instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 87%) was obtained as colorless crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08492378B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-0c8b8bcbbb254e52b8b751ad2659e22a |
| 出典メモ | uspto-grants-2013_07 |