化工社化工社 化学情報印刷レポート · 研究参考用
Metformin Hydrochloride → HCID 178476642、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Metformin Hydrochloride | HCID 14219 | — |
| 反応物 | Sodium Acetate Trihydrate | HCID 23665404 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | HCID 178476642 | HCID 178476642 | 51.6% |
反応手順
20.0 g (1 equivalent) of metformin hydrochloride, 50 Ml of water, and 19.72 g (1.2 equivalents) of sodium acetate trihydrate were added to a reactor, and stirred. Then the resulting crystal was filtered and washed with acetone, and then dried at 60° C. to obtain 11.72 g of metformin acetate (yield: 51.3%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08541474B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-8f6f02ec54e8446e91f4b5525381d122 |
| 出典メモ | uspto-grants-2013_09 |