化工社化工社 化学情報印刷レポート · 研究参考用
Benzylamine → 2-Amino-4-methylthiazole-5-carboxylic Acid 4-Chlorobenzylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzylamine | HCID 7504 | — |
| 反応物 | 4-Chlorobenzylamine | HCID 66036 | — |
| 反応物 | 2-Amino-4-methyl-thiazole-5-carboxylic acid | HCID 832243 | — |
| 生成物 | 2-Amino-4-methylthiazole-5-carboxylic Acid 4-Chlorobenzylamide | HCID 62793398 | 15% |
反応手順
Following the procedure as described in Preparation 1, making variation only as required to use 4-chlorobenzylamine to replace benzylamine to react with 2-amino-4-methylthiazole-5-carboxylic acid, the title compound was obtained as a white solid in 15% yield; 1H NMR (CD3OD, 300 MHz) δ 7.26-7.32 (m, 4H), 4.41 (s, 2H), 2.38 (s, 3H). MS (ES+) m/z 282.1 (M+1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08541457B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-71a0d48e151b4f408c37694c52a3b666 |
| 出典メモ | uspto-grants-2013_09 |