化工社化工社 化学情報印刷レポート · 研究参考用
Epichlorohydrin → 4-(2,3-Epoxypropoxy)salicylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Epichlorohydrin | HCID 7835 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Methyl 2,4-Dihydroxybenzoate | HCID 16523 | — |
| 生成物 | 4-(2,3-Epoxypropoxy)salicylic acid methyl ester | HCID 12611335 | — |
反応手順
By refluxing 34 g of 2,4-dihydroxybenzoic acid methyl ester with 185 g of epichlorohydrin and 35 g of potassium carbonate for 2 to 3 hours, and chromatographing the crude product on 100 g of silica gel (elution with toluene), 4-(2,3-epoxypropoxy)salicylic acid methyl ester having a melting point of 53°-55° is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04727067 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-04f489d6f4b84e0caced2494d503c25d |
| 出典メモ | uspto-grants-1988_02 |