2-Methylpropanimidamide hydrochloride → HCID 178440336、化合物

HRID 455144

反応式

HRID 455144 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][N:11]3[C:16]=2[CH2:17][C:18]2[NH:22][C:21]([C:23]3[CH:28]=CC=CN=3)=[N:20][N:19]=2)=[CH:4][CH:3]=1.Cl[C:30]1C=CC(C2N=C3C=CC=CN3C=2CC(NN)=O)=CC=1.Cl.C(=N)(N)C(C)C>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][N:11]3[C:16]=2[CH2:17][C:18]2[NH:22][C:21]([CH:23]([CH3:30])[CH3:28])=[N:20][N:19]=2)=[CH:6][CH:7]=1

参加物

4

反応物 3

HCID 27820532-Methylpropanimidamide hydrochlorideHCID 670291592-(2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetohydrazideHCID 178477970HCID 178477970、化合物

生成物 1

HCID 178440336HCID 178440336、化合物

実験手順

The title compound was prepared according to the experimental described for compound 230 from 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetohydrazide and isobutyrimidamide hydrochloride. M/e+ 352 for C19H19ClN5 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.05 (m, 1H), 7.61 (d, J=8.4 Hz, 2H), 7.27 (m, 4H), 7.04 (t, J=7.3 Hz, 1H), 6.75 (t, J=6.6 Hz, 1H), 4.42 (s, 2H), 3.12 (m, 1H), 1.39 (s, 3H), 1.37 (s, 3H) ppm.

出典と根拠

ORDレコード
ord-85e5e14804224826a84cef6a181ef1de
出典データセット
uspto-grants-2013_07
特許番号
US08497278B2

関連ノート

読み込み中…