Phenol → 1-[3-(4-Bromo-phenyl)-3-phenoxy-propyl]-1H-imidazole

反応式

[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:8][C:9]1[CH:14]=[CH:13][C:12]([CH:15](O)[CH2:16][CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[CH:19]2)=[CH:11][CH:10]=1>>[Br:8][C:9]1[CH:14]=[CH:13][C:12]([CH:15]([O:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:16][CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[CH:19]2)=[CH:11][CH:10]=1

参加物

反応物 2

HCID 996Phenol

HCID 214153621-(4-Bromo-phenyl)-3-imidazol-1-yl-propan-1-ol

生成物 1

HCID 593319531-[3-(4-Bromo-phenyl)-3-phenoxy-propyl]-1H-imidazole

実験手順

Phenol was reacted with 1-(4-Bromo-phenyl)-3-imidazol-1-yl-propan-1-ol* following the procedure set out in Example 48B to give the title compound. LC/MS: (PS-A2) Rt 2.30 [M+H]+ 357.26, 359.27.

出典と根拠

ORDレコード: ord-ab6aedfa9d064800a13bf4df35c2cf0e
出典データセット: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08541461B2

反応ノート

読み込み中…