化工社化工社 化学情報印刷レポート · 研究参考用
4-Fluorophenethyl Alcohol → N-{4-[2-(4-Fluorophenyl)ethoxy]benzoyl}glycine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Fluorophenethyl Alcohol | HCID 82068 | — |
| 反応物 | N-(4-Hydroxybenzoyl)glycine tert-butyl ester | HCID 10682169 | — |
| 生成物 | N-{4-[2-(4-Fluorophenyl)ethoxy]benzoyl}glycine | HCID 66812288 | 91% |
反応手順
The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (249 mg, 0.991 mmol) prepared in Example 1 (1a) and 2-(4-fluorophenyl)ethanol (150 μL, 1.20 mmol) to give 241 mg of the title compound (yield: 91%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08497397B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-6afa8e6ef7d241f0aba772375422b751 |
| 出典メモ | uspto-grants-2013_07 |