3,3'-Diaminobenzidine → HCID 18436489、化合物

HRID 456362

反応式

HRID 456362 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[C:11]([NH2:16])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[NH2:8]>C1(=O)CCCCC1>[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[NH2:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[C:11]([NH2:16])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[NH2:8]

参加物

3

反応物 1

HCID 70713,3'-Diaminobenzidine

生成物 1

HCID 18436489HCID 18436489、化合物収率 90%

試薬・触媒・溶媒 1

HCID 7967Cyclohexanone溶媒

反応条件

温度
60 °C

実験手順

In a 200-ml flask equipped with a stirrer, a condenser and a thermometer were placed 21.4 g (100 mmol) of 3,3′-diaminobenzidine and 100 ml of cyclohexanone, followed by heating with stirring at 60° C. in a nitrogen atmosphere for 2 hours. After cooling to room temperature, cyclohexanone was removed under reduced pressure. The residue was purified by silica gel chromatography, to yield 48.1 g (90 mmol) of the target 3,3′-diaminobenzidine tetracyclohexanimine [N,N′,N″,N′″-tetracyclohexylidene-3,4,3′,4′-biphenyltetramine] in a yield of 90%.

後処理

  1. customIn a 200-ml flask equipped with a stirrer, a condenser
  2. temperatureby heating
  3. temperatureAfter cooling to room temperature
  4. customcyclohexanone was removed under reduced pressure
  5. customThe residue was purified by silica gel chromatography

出典と根拠

ORDレコード
ord-a4e875c34afd4f75a4db895afccd1b3b
出典データセット
uspto-grants-2007_03
特許番号
US07186454B2

関連ノート

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