3,3'-Diaminobenzidine → 3,3'-Diaminobenzidine tetracyclohexanimine
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[C:11]([NH2:16])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[NH2:8]>C1(=O)CCCCC1>[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[C:2]1(=[NH:1])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[NH2:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[C:11]([NH2:16])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[NH2:8]参加物
3
反応条件
- 温度
- 60 °C
実験手順
In a 200-ml flask equipped with a stirrer, a condenser and a thermometer were placed 21.4 g (100 mmol) of 3,3′-diaminobenzidine and 100 ml of cyclohexanone, followed by heating with stirring at 60° C. in a nitrogen atmosphere for 2 hours. After cooling to room temperature, cyclohexanone was removed under reduced pressure. The residue was purified by silica gel chromatography, to yield 48.1 g (90 mmol) of the target 3,3′-diaminobenzidine tetracyclohexanimine [N,N′,N″,N′″-tetracyclohexylidene-3,4,3′,4′-biphenyltetramine] in a yield of 90%.