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3-Piperidinol, 1-methyl- → 4-[2-(1-Methyl-piperidin-3-yloxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Piperidinol, 1-methyl- | HCID 98016 | — |
| 反応物 | Tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylate | HCID 11543684 | — |
| 反応物 | 4-[2-(2-Morpholin-4-yl-ethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 18436764 | — |
| 生成物 | 4-[2-(1-Methyl-piperidin-3-yloxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 69417223 | — |
反応手順
The title compound was prepared in a manner similar to 4-[2(2-Morpholin-4-yl-ethoxy)-phenyl]-piperazine-1-carboxylicacid tert-butyl ester except that 4-(2-hydroxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester was coupled to 1-methyl-piperidin-3-ol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07186715B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-018fbdc1147f474b85b3273ed44ec37e |
| 出典メモ | uspto-grants-2007_03 |