化工社化工社 化学情報印刷レポート · 研究参考用
Ammonium Hydroxide → 3,5-Dichloro-3-pyridylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonium Hydroxide | HCID 14923 | — |
| 反応物 | Pyridine, 2,3,5-trichloro- | HCID 27666 | — |
| 生成物 | 3,5-Dichloro-3-pyridylamine | HCID 77886 | — |
反応手順
2,3,5-Trichloropyridine (20 g, 0.11 moles) was placed in a steel bomb and treated with ammonium hydroxide (300 mL) at 190° C. in similar manner as described in Example 2 to give 2-amino-3,5-dichloropyridine (15 g) as a white solid. 1H NMR (CDCl3) δ 7.92 (d, 1H), 7.48 (d, 1H), 5.1 (broad s, 2H); MS m/z 163 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07186714B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-e4551d28495c451cb2bebf3e0561a601 |
| 出典メモ | uspto-grants-2007_03 |