化工社化工社 化学情報印刷レポート · 研究参考用
Water → 5-Bromo-6-methoxy-2-methylthioquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 5-Bromo-2-methanesulfonyl-6-methoxy-quinoline | HCID 22139732 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 5-Bromo-6-methoxy-2-methylthioquinoline | HCID 22139696 | — |
反応手順
The 5-bromo-2-methanesulfonyl-6-methoxy-quinoline was dissolved in 20 mL DMF and treated with 3 eq NaSCH3. After stirring 1 hour at room temperature the mixture was poured into water and extracted with ether. The crystalline product, 5-bromo-6-methoxy-2-methylsulfanyl-quinoline, was isolated in quantitative yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07186840B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-8542729a995243a999855b2982dc87ae |
| 出典メモ | uspto-grants-2007_03 |