Bromine → 3-Bromo-1,1-dimethoxypropan-2-one

HRID 457393

反応式

HRID 457393 の反応式
[Br:1]Br.[CH3:3][O:4][CH:5]([O:9][CH3:10])[C:6](=[O:8])[CH3:7]>CO>[Br:1][CH2:7][C:6](=[O:8])[CH:5]([O:9][CH3:10])[O:4][CH3:3]

参加物

4

反応物 2

HCID 24408BromineHCID 80650Pyruvic aldehyde dimethyl acetal

生成物 1

HCID 120035673-Bromo-1,1-dimethoxypropan-2-one

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Bromine (80 g, 0.5 mol) is added dropwise to a solution of 1,1-dimethoxy-propan-2-one 205 (59 g, 0.5 mol) in anhydrous methanol (400 mL) at 0° C. and the solution is continued stirring at room temperature for 48 h. The solvent is removed under reduced pressure and the residue is dried in vacuo and used without further purification.

後処理

  1. customThe solvent is removed under reduced pressure
  2. customthe residue is dried in vacuo
  3. customused without further purification

出典と根拠

ORDレコード
ord-189330a0d2cb478a9470be0fe0c6286d
出典データセット
uspto-grants-2007_03
特許番号
US07186734B2

関連ノート

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