関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 5-Chlorosalicylic Acid | HCID 9447 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 溶媒 | Heptane | HCID 8900 | — |
| 生成物 | 5-Chloro-2-hydroxybenzoyl chloride | HCID 12863233 | 99.3% |
反応手順
A solution of 5-chloro-2-hydroxy-benzoic acid (20.0 g, 116 mmol) in heptane (232 mL, 0.5 M) was treated with thionyl chloride (25.4 mL, 348 mmol) and heated to 60° C. for 6 h. After cooling to room temperature, the solution was concentrated under reduced pressure to give 5-chloro-2-hydroxy-benzoyl chloride as a thick yellow oil (22 g) which was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07189749B2 |
|---|
| 出典データセット | uspto-grants-2007_03 |
|---|
| ORD ID | ord-a2eab2155d4c4b518cbf2bcd1b497a70 |
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| 出典メモ | uspto-grants-2007_03 |
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