Benzyl Bromide → 7-Benzyl-8-bromo-3-methylxanthine

反応式

[Br:1][C:2]1[NH:10][C:9]2[C:8](=[O:11])[NH:7][C:6](=[O:12])[N:5]([CH3:13])[C:4]=2[N:3]=1.[CH2:14](Br)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([N:10]1[C:9]2[C:8](=[O:11])[NH:7][C:6](=[O:12])[N:5]([CH3:13])[C:4]=2[N:3]=[C:2]1[Br:1])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

参加物

反応物 2

HCID 7498Benzyl Bromide

HCID 15487978-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione

生成物 1

HCID 8361527-Benzyl-8-bromo-3-methylxanthine

実験手順

8-Bromo-3-methyl-3,7-dihydropurine-2,6-dione and benzyl bromide were reacted and purified as described in the General procedure G, step A, to afford 77A.

後処理

custompurified

出典と根拠

ORDレコード: ord-5c5fedc3df8b401382154178b16ca767
出典データセット: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07192952B2

反応ノート

読み込み中…