8-Chlorotheophylline → Purine-2,6(1H,3H)-dione, 7-(2-bromobenzyl)-8-chloro-1,3-dimethyl-

HRID 458642

反応式

HRID 458642 の反応式
[Cl:1][C:2]1[NH:11][C:10]2[C:9](=[O:12])[N:7]([CH3:8])[C:6](=[O:13])[N:5]([CH3:14])[C:4]=2[N:3]=1.[Br:15][C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18]Br>>[Br:15][C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18][N:11]1[C:10]2[C:9](=[O:12])[N:7]([CH3:8])[C:6](=[O:13])[N:5]([CH3:14])[C:4]=2[N:3]=[C:2]1[Cl:1]

参加物

3

反応物 2

HCID 106618-ChlorotheophyllineHCID 769652-Bromobenzyl bromide

生成物 1

HCID 598207Purine-2,6(1H,3H)-dione, 7-(2-bromobenzyl)-8-chloro-1,3-dimethyl-

実験手順

8-Chlorotheophylline and 2-bromobenzyl bromide were reacted and purified as described in the General procedure CC, step A, to afford 83A as white crystals in 57%.

後処理

  1. custompurified

出典と根拠

ORDレコード
ord-436bb6249511462fb9c4d8d843289b89
出典データセット
uspto-grants-2007_03
特許番号
US07192952B2

関連ノート

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