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4-Cyclopentylphenol → (2S)-3-{4-[3-(4-Cyclopentyl-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Cyclopentylphenol | HCID 15202 | — |
| 反応物 | (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid | HCID 69424952 | — |
| 生成物 | (2S)-3-{4-[3-(4-Cyclopentyl-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid | HCID 58822587 | — |
反応手順
The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 4-cyclopentylphenol and cleavage from the resin (Standard Procedure G) gave an oily solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07192982B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-0fd99128642746fa9ef53d89a733600b |
| 出典メモ | uspto-grants-2007_03 |