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4-Phenoxyphenol → 2-Methoxy-3-{4-[2-(4-phenoxy-phenoxy)-ethoxy]-phenyl}-propionic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Phenoxyphenol | HCID 13254 | — |
| 反応物 | (2S)-3-{4-[2-(biphenyl-4-yloxy)-ethoxy]-phenyl}-2-methoxy-propionic acid | HCID 10135109 | — |
| 反応物 | (2S)-3-[4-(2-bromo-ethoxy)-phenyl]2-methoxy-propionic acid ethyl ester | HCID 58822865 | — |
| 生成物 | 2-Methoxy-3-{4-[2-(4-phenoxy-phenoxy)-ethoxy]-phenyl}-propionic acid | HCID 18443171 | — |
反応手順
The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 283, Step 2) and 4-phenoxy-phenol via the same procedure used for the preparation of (2S)-3-{4-[2-(biphenyl-4-yloxy)-ethoxy]-phenyl}-2-methoxy-propionic acid (Example 283, Step 3) to produce a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07192982B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-83e4c4f262604b95bb4b15153e5b39f7 |
| 出典メモ | uspto-grants-2007_03 |