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7-Hydroxyflavone → (2S)-2-methoxy-3-{4-[2-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-ethoxy]-phenyl}-propionic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 7-Hydroxyflavone | HCID 5281894 | — |
| 反応物 | (2S)-3-[4-(2-bromo-ethoxy)-phenyl]2-methoxy-propionic acid ethyl ester | HCID 58822865 | — |
| 反応物 | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| 生成物 | (2S)-2-methoxy-3-{4-[2-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-ethoxy]-phenyl}-propionic acid | HCID 58822724 | — |
反応手順
The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 283, Step 2) and 7-hydroxy-2-phenyl-chromen-4-one via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a yellow solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07192982B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-7cf6778a5b3d477caaf417a3e86ae370 |
| 出典メモ | uspto-grants-2007_03 |