2,6-Diaminopyridine → HCID 69410957、化合物

反応式

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9]1[CH:14]=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[N:18]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9]1[CH2:14][NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[N:18]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

参加物

反応物 2

HCID 88612,6-Diaminopyridine

HCID 10656219tert-Butyl 2-formylpiperidine-1-carboxylate

生成物 1

HCID 69410957HCID 69410957、化合物

実験手順

In a manner similar to that described in Preparation CD, 2-formyl-piperidine-1-carboxylic acid tert-butyl ester (360 mg, 1.69 mmol) was treated with 2,6-diaminopyridine (184 mg, 1.69 mmol) and stirred at RT to give a light brown oil. MS m/z: 307.3(M+H). Calc'd. for C16H26N4O2-306.21.

後処理

customto give a light brown oil

出典と根拠

ORDレコード: ord-fbcd8bbb56c7421dbc80a3a1ac4c0888
出典データセット: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07196104B2

反応ノート

読み込み中…

参加物