関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Cyclohexyl methyl ketone | HCID 13207 | — |
| 反応物 | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| 生成物 | 1-Cyclohexyl-3-dimethylamino-propenone | HCID 11095241 | 93% |
反応手順
A mixture of 3.0 g (23.8 mmol) of cyclohexyl methyl ketone and 4.56 g (26.2 mmol) of t-butoxybis(dimethylamino)methane (Bredereck's reagent) was stirred at 60° C. overnight. The reaction mixture was then concentrated to give 4.0 g (93% yield) of 1-cyclohexyl-3-dimethylamino-propenone as an orange oil as indicated by 1H NMR. This product was used in the next reaction without any further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US07196111B2 |
|---|
| 出典データセット | uspto-grants-2007_03 |
|---|
| ORD ID | ord-cbb6055354164bfe8509e4c4b6195761 |
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| 出典メモ | uspto-grants-2007_03 |
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