Carbamic acid, methylthio-, O-ethyl ester → HCID 53685992、化合物

HRID 460766ノート

反応式

HRID 460766 の反応式
[C:1]([CH:9](Br)[CH2:10][CH2:11][Cl:12])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:14][NH:15][C:16](=[S:20])[O:17]CC>O1CCOCC1>[CH3:14][N:15]1[C:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:9]([CH2:10][CH2:11][Cl:12])[S:20][C:16]1=[O:17]

参加物

4

反応物 2

HCID 5365210Carbamic acid, methylthio-, O-ethyl esterHCID 202266952-Bromo-4-chloro-1-phenylbutan-1-one

生成物 1

HCID 53685992HCID 53685992、化合物

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

The 3-methyl-4-phenyl-5-β-chloroethyl-4-thiazolin-2-one is prepared in the following manner. A solution of 21.9 g of 1-benzoyl-1-bromo-3-chloropropane and 5 g of ethyl N-methyl-thiocarbamate in 50 cc of dioxan is heated under reflux for 10 hours, and then evaporated to dryness under reduced pressure, M.P. = 88°-90° C (from hexane).

後処理

  1. temperatureunder reflux for 10 hours
  2. customevaporated to dryness under reduced pressure, M.P. = 88°-90° C (from hexane)

出典と根拠

ORDレコード
ord-0d9b4d975bcd44089a07243b51c2491b
出典データセット
uspto-grants-1977_12
特許番号
US04061637

反応ノート

読み込み中…