2,3',4'-Trichloro-5'-sulfamoylacetophenone → 3-(3,4-Dichloro-5-sulfamoylphenyl)-3-hydroxy-2,3,6,7-tetrahydro-5H-thiazolo[3,2-a]-pyrimidine-hydrochloride
反応式
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([Cl:15])=[C:7]([Cl:16])[CH:6]=1)=[O:4].[N:17]1[CH2:22][CH2:21][CH2:20][NH:19][C:18]=1[SH:23]>>[ClH:1].[Cl:16][C:7]1[CH:6]=[C:5]([C:3]2([OH:4])[N:19]3[CH2:20][CH2:21][CH2:22][N:17]=[C:18]3[S:23][CH2:2]2)[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]=1[Cl:15]参加物
3
実験手順
was obtained in a manner analogous to the method described in Example 1 d from 2,3',4'-trichloro-5'-sulfamoyl-acetophenone and 2,35 g of 3,4,5,6-tetrahydro-2-pyrimidine-thiol. M.p. 188° C (decomposition).
後処理
- customwas obtained in a manner analogous to the method
出典と根拠
- ORDレコード
- ord-595875bea0214508b82acbc21ca0a57a
- 出典データセット
- uspto-grants-1977_12
- 特許番号
- US04061647
反応ノート
読み込み中…