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Dicyclohexylthiourea → 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-cyclohexyl-2-cyclohexylimino-1,3-thiazolidine-4-ol-hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dicyclohexylthiourea | HCID 727200 | — |
| 反応物 | 2-Bromo-2',4'-dichloro-5'-sulfamoylacetophenone | HCID 22756429 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-cyclohexyl-2-cyclohexylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 21394764 | — |
反応手順
2.4 g of 1,3-dicyclohexyl-thiourea were added to 3,5 g of 2-bromo-2',4'-dichloro-5'-sulfamoylacetophenone in 40 ml of ethyl acetate. The whole was allowed to stand overnight at 20° C, the crystals were filtered off and washed with ethyl acetate. M.p. 161°-163° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04061647 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-208c8c3e928e44cca51f415e62697259 |
| 出典メモ | uspto-grants-1977_12 |