Triphenylphosphine → (2,5-Dimethyl-3-thenyl)triphenylphosphonium chloride

HRID 460953

反応式

HRID 460953 の反応式
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:20][C:21]1[S:22][C:23]([CH3:28])=[CH:24][C:25]=1[CH2:26][Cl:27]>C1(C)C=CC=CC=1>[Cl-:27].[CH3:20][C:21]1[S:22][C:23]([CH3:28])=[CH:24][C:25]=1[CH2:26][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

参加物

4

反応物 2

HCID 11776TriphenylphosphineHCID 128752613-(Chloromethyl)-2,5-dimethylthiophene

生成物 1

HCID 20285688(2,5-Dimethyl-3-thenyl)triphenylphosphonium chloride

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Triphenylphosphine (11.8 g.) and 7.0 g. of 2,5-dimethyl-3-chloromethylthiophene were dissolved in 100 ml. of toluene. The mixture was refluxed overnight under argon, cooled to room temperature and the precipitated white phosphonium salt was collected by filtration, washed several times with cold benzene and dried at 80° C. under high vacuum. The resulting (2,5-dimethyl-3-thenyl)-triphenylphosphonium chloride has a m.p. 246°-250° C.

後処理

  1. temperatureThe mixture was refluxed overnight under argon
  2. filtrationthe precipitated white phosphonium salt was collected by filtration
  3. washwashed several times with cold benzene
  4. customdried at 80° C. under high vacuum

出典と根拠

ORDレコード
ord-77bac11b374d4b569275e985baa2db7f
出典データセット
uspto-grants-1977_12
特許番号
US04061656

関連ノート

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