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Acetic Anhydride → Diethyl 5-acetamido-3-methylthiophene-2,4-dicarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | Diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate | HCID 78537 | — |
| 生成物 | Diethyl 5-acetamido-3-methylthiophene-2,4-dicarboxylate | HCID 291812 | — |
反応手順
A solution of 23.0 g. (0.09 mol) of 2,4-diethoxycarbonyl-3-methyl-5-aminothiophene in 250 ml. of acetic anhydride was heated to 100° C. for 1.5 hrs. The resulting mixture was cooled in an ice bath and the precipitated crystals were filtered to yield 2,4-diethoxycarbonyl-3-methyl-5-acetylamino-thiophene, m.p. 130°-131° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04061656 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-ca6932ddd2f341b8b430cbd38161b4b3 |
| 出典メモ | uspto-grants-1977_12 |