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Bromo-4'-chloro-3'-sulfamoylacetophenone → 4-(4-Chloro-3-sulfamoylphenyl)-2-isopropylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromo-4'-chloro-3'-sulfamoylacetophenone | HCID 12952390 | — |
| 反応物 | 1-Methyl-3-isopropylthiourea | HCID 14229900 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 4-(4-Chloro-3-sulfamoylphenyl)-2-isopropylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide | HCID 22760466 | — |
反応手順
6.1 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone were heated with 2.4 g of 1-methyl-3-isopropylthiourea in 50 ml of acetone for 10 minutes to 40° C, the separating oil was triturated to form crystals and the crystalline suspension was stirred for 1 hour at room temperature. Colorless solid body: melting point: 195° C (decomposition).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04061761 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-32104b1699e44898ad55d752a12d86bc |
| 出典メモ | uspto-grants-1977_12 |