Bromo-4'-chloro-3'-sulfamoylacetophenone → 4-(4-Chloro-3-sulfamoylphenyl)-2-isobutylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide

HRID 461122

反応式

HRID 461122 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:11])[CH2:9][Br:10])=[CH:4][C:3]=1[S:12](=[O:15])(=[O:14])[NH2:13].[CH2:16]([NH:20][C:21]([NH:23][CH3:24])=[S:22])[CH:17]([CH3:19])[CH3:18]>>[BrH:10].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:11])[CH2:9][S:22][C:21](=[N:20][CH2:16][CH:17]([CH3:19])[CH3:18])[N:23]2[CH3:24])=[CH:4][C:3]=1[S:12](=[O:15])(=[O:14])[NH2:13]

参加物

3

反応物 2

HCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenoneHCID 155682431-Isobutyl-3-methylthiourea

生成物 1

HCID 227604724-(4-Chloro-3-sulfamoylphenyl)-2-isobutylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide

実験手順

6.2 g of 4'-chloro-3'-sulfamoyl-2-bromoacetophenone and 3.0 g of 1-isobutyl-3-methylthiourea were reacted according to the prescription made in Example 23 and the colorless end product was precipitated with 200 ml of diethyl ether.

後処理

  1. customthe colorless end product was precipitated with 200 ml of diethyl ether

出典と根拠

ORDレコード
ord-3030b07c7e8244d4aca4cef3dee0274f
出典データセット
uspto-grants-1977_12
特許番号
US04061761

関連ノート

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