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N,N'-Diethylthiourea → 3-Ethyl-2-ethylimino-4-(4-methyl-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N'-Diethylthiourea | HCID 2735009 | — |
| 反応物 | 2-Chloro-4'-methyl-3'-sulfamoylacetophenone | HCID 13628783 | — |
| 溶媒 | Diisopropyl Ether | HCID 7914 | — |
| 生成物 | 3-Ethyl-2-ethylimino-4-(4-methyl-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride | HCID 22760433 | — |
反応手順
5 g of 2-chloro-4'-methyl-3'-sulfamoylacetophenone and 2.7 g of 1,3-diethylthiourea were reacted as prescribed in Example 12. After addition of 200 ml of diisopropyl ether the solvent was decanted and the oily end product was crystallized under ethyl acetate heated to 40° to 50° C. Colorless solid body, melting point: 160° C (decomposition).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04061761 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-31fcc2290c774320bcc607a62f00ec11 |
| 出典メモ | uspto-grants-1977_12 |