Dimethylamine → HCID 22760438、化合物

HRID 461191ノート

反応式

HRID 461191 の反応式
[CH3:1][NH:2][CH3:3].CO.[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][C:8]=1[S:16](Cl)(=[O:18])=[O:17]>O>[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][C:8]=1[S:16](=[O:17])(=[O:18])[N:2]([CH3:3])[CH3:1]

参加物

5

反応物 3

HCID 674DimethylamineHCID 887MethanolHCID 126197955-Acetyl-2-chlorobenzene-1-sulfonyl chloride

生成物 1

HCID 22760438HCID 22760438、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
60 °C

実験手順

To a stirred mixture of 10 ml of 40% dimethyl amine solution and 60 ml of methanol, there were added, portionswise, 5.1 g of 4'-chloro-3'-chlorosulfonylacetophenone, so that the reaction temperature did not exceed 30° C. The reaction mixture was stirred for 3 hours at room temperature and 15 minutes at 60° C. After cooling, the reaction mixture was poured into 200 ml of water and the crystals were filtered off. Melting point: 108° C.

後処理

  1. additionwere added
  2. customdid not exceed 30° C
  3. temperatureAfter cooling
  4. filtrationthe crystals were filtered off

出典と根拠

ORDレコード
ord-ab96505f96444dcd888e4ac1b02ab2e3
出典データセット
uspto-grants-1977_12
特許番号
US04061761

反応ノート

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