化工社化工社 化学情報印刷レポート · 研究参考用
Magnesium peroxide (Mg(O2)) → 2-Chloro-3-methylbenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Magnesium peroxide (Mg(O2)) | HCID 61745 | — |
| 反応物 | 2-Chloro-3-methylbenzoic acid | HCID 139879 | — |
| 反応物 | Diboron | HCID 6328200 | — |
| 反応物 | (2-Chloro-3-methylphenyl)methanol | HCID 14534589 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2-Chloro-3-methylbenzaldehyde | HCID 14492779 | — |
反応手順
2-Chloro-3-methylbenzoic acid was reduced by treating with diborane in tetrahydrofuran and the resulting 2-chloro-3-methylbenzyl alcohol was oxidized with activated magnesium dioxide in methylene chloride to give 2-chloro-3-methylbenzaldehyde.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04062961 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-e128f60000ba484d87be01489aa5d34b |
| 出典メモ | uspto-grants-1977_12 |