Ammonia → 2,6-Dinitro-4-(trifluoromethyl)aniline
反応式
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[NH3:18].C(O)C>C(OCC)(=O)C>[NH2:18][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16]参加物
5
実験手順
Twenty six grams (0.096m) of crude 4-chloro-3,5-dinitrobenzotrifluoride, 150 ml. of liquid ammonia and 150 ml. of 2B ethanol were heated in a sealed autoclave at 100° C. for about 4 hours. After cooling and venting, the reaction mixture was taken up in ethyl acetate. The ethyl acetate phase was washed with water. The ethyl acetate solution was dried and evaporated in vacuo to yield crude 4-amino-3,5-dinitrobenzotrifluoride.
後処理
- temperatureAfter cooling
- washThe ethyl acetate phase was washed with water
- dry with materialThe ethyl acetate solution was dried
- customevaporated in vacuo
出典と根拠
- ORDレコード
- ord-6c74e5568ac744b987452968520ce2e3
- 出典データセット
- uspto-grants-1977_12
- 特許番号
- US04064127
反応ノート
読み込み中…