Ammonia → 2,6-Dinitro-4-(trifluoromethyl)aniline

HRID 461666

反応式

HRID 461666 の反応式
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[NH3:18].C(O)C>C(OCC)(=O)C>[NH2:18][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16]

参加物

5

反応物 3

HCID 222AmmoniaHCID 702EthanolHCID 98094-Chloro-3,5-dinitrobenzotrifluoride

生成物 1

HCID 99362,6-Dinitro-4-(trifluoromethyl)aniline

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

Twenty six grams (0.096m) of crude 4-chloro-3,5-dinitrobenzotrifluoride, 150 ml. of liquid ammonia and 150 ml. of 2B ethanol were heated in a sealed autoclave at 100° C. for about 4 hours. After cooling and venting, the reaction mixture was taken up in ethyl acetate. The ethyl acetate phase was washed with water. The ethyl acetate solution was dried and evaporated in vacuo to yield crude 4-amino-3,5-dinitrobenzotrifluoride.

後処理

  1. temperatureAfter cooling
  2. washThe ethyl acetate phase was washed with water
  3. dry with materialThe ethyl acetate solution was dried
  4. customevaporated in vacuo

出典と根拠

ORDレコード
ord-6c74e5568ac744b987452968520ce2e3
出典データセット
uspto-grants-1977_12
特許番号
US04064127

関連ノート

読み込み中…