化工社化工社 化学情報印刷レポート · 研究参考用
Acetylalanylalanylleucine benzyl ester → Acetylalanylalanylleucine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetylalanylalanylleucine benzyl ester | HCID 54388809 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Acetylalanylalanylleucine | HCID 54064604 | — |
反応手順
Acetylalanylalanylleucine benzyl ester (2 mmole) is dissolved in denaturated ethyl alcohol (0.5 gal. benzene added to 100 gal. of absolute ethanol) (15 ml) and hydrogenated over 10% palladium/charcoal (0.1 gm) at 40 psi for 1/2 hour. The solution was filtered through Celite and evaporated in vacuo. The residue is triturated with diethyl ether to give crystalline acetylalanylalanylleucine, m.p. 185°-186°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04064236 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-4a39032193a84006bd99d2a29fe53003 |
| 出典メモ | uspto-grants-1977_12 |