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p-Acetoxybenzoyl chloride → 4-Acetoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | p-Acetoxybenzoyl chloride | HCID 2756254 | — |
| 反応物 | 2-(2-Aminophenethyl)-1-methylpiperidine | HCID 11085282 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 4-Acetoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide | HCID 20560030 | — |
反応手順
Reaction of 2-(o-aminophenethyl)-1-methylpiperidine with p-acetoxybenzoyl chloride in pyridine according to Example 1 provides 4-acetoxy-2'-[2-(1-methyl-2-piperidyl)-ethyl]benzanilide. Analytically pure product is obtained by crystallization from isopropyl ether, m.p. 88°-108° C. (corr.). The broad melting point of the analytically pure material is due to polymorphism.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04064254 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-71b55c2e83f747ee9807e6e6ee065a50 |
| 出典メモ | uspto-grants-1977_12 |