化工社化工社 化学情報印刷レポート · 研究参考用
(4-Aminophenoxy)benzene → 1-(4-Phenoxyphenyl)piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Aminophenoxy)benzene | HCID 8764 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | Bis(2-bromoethyl)amine | HCID 415719 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 1-(4-Phenoxyphenyl)piperazine | HCID 3017356 | — |
反応手順
To a solution of 62.4 parts of bis-(β-bromoethyl)amine dihybromide in 160 parts of methanol there were added 37 parts of para-phenoxyaniline. The mixture was refluxed for 10 hours. 10.6 parts of Na2CO3 were then added and the reaction mixture was refluxed for a further 10 hours. After cooling, the precipitate was filtered off, washed with 80 parts of methanol and dried.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04064245 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-2368a7cc6aa643bf82c15e20288aef90 |
| 出典メモ | uspto-grants-1977_12 |